Southern Polytechnic State University is approximately 20 minutes from downtown Atlanta.  The university is located one mile west of I-75's exit 263, (120 Loop), at 1100 South Marietta Parkway, Marietta, GA.

SPSU can also be accessed from Cobb Parkway, (41), by turning west at Cobb Parkway and South Marietta Parkway, and from Atlanta Road/Roswell Road (120) to the 120 Loop west bound.